Helicobacter pylori IgG/A Serological Testing

Improve sensitivity and specificity for the most virulent strains with GSD’s H. pylori EIA kit.

Gold Standard Diagnostics H. pylori IgG and IgA ELISA tests offer excellent sensitivity and specificity, especially for the more virulent CagA and VacA strains of H. pylori.

Research has demonstrated a link between strains that express CagA and VacA antigen, and increased risk of gastric cancer1 and ulcer2. H. pylori serological testing detects the most virulent strains that express CagA and VacA antigens.

Gold Standard Diagnostics H. pylori EIA’s are manufactured using a proprietary antigen and purification process developed by an H. pylori specialist from the Institute for Medical Microbiology and Hygiene in Germany.

GSD H. pylori Serological Testing Advantages

Non-invasive and cost-effective… Best option for pre-treatment diagnosis.

Key Benefits:

  • FDA Cleared
  • Excellent sensitivity & specificity.
  • Detects CagA & VacA positive strains.
  • Best option for pre-treatment testing.
  • Non-invasive and low cost compared to other diagnostic methods.

H. pylori Diagnostics Studies

  1. Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori. Leen-Jan van Doorn, Ceu Figueiredo, Ricardo Sanna, Anton Plaisier, Peter Schneeberger, Wink de Boer, Wim Quint. Received 10 December 1997; accepted 13 March 1998.Gastroenterology Volume 115, Issue 1 , Pages 58-66, July 1998.
  2. Risk for gastric cancer in people with CagA positive or CagA negativeHelicobacter pylori infection. J Parsonnet, G D Friedman, N Orentreich, H Vogelman Gut 1997;40:297-301 doi:10.1136/gut.40.3.297
  3. Helicobacter pylori infection and the development of gastric cancer. Uemura N, Okamoto S, Yamamoto S, Matsumura N, Yamaguchi ,Yamakido M, Taniyama K, Sasaki N, Schlemper RJ. N Engl J Med. 2001 Sep 13;345(11):784-9.
  4. CagA+ Helicobacter pylori infection and gastric cancer risk in the EPIC-EURGAST study. CA Gonzalez et al., Int J Cancer, February 15, 2007; 120(4):859-67
  5. Combined serum IgG response to Helicobacter pylori VacA and CagA predicts gastric Cancer. LP Andersen et al., FEMS Immunol Med Microbiol, July 1, 2007;50(2):220-5